Figure 2
From: Survivin Expression in Tuberous Sclerosis Complex Cells
Two types of purified TSC2 cells. Exposure to an β-actin antibody (a, b) specific for smooth muscle cells showed that the antigen was present in flat, elongated TSC2−/− cells (A+) but undetectable in epithelioid TSC2+/− cells (R+). Rho-A was very abundant in R+ cells (a′,b′), which were labeled with the anti-keratin 8/18 antibody (b′′). No anti-keratin 8/18 labeling was observed in A+ cells (a′′).