Figure 1
From: Zinc Inhibits Astrocyte Glutamate Uptake by Activation of Poly(ADP-ribose) Polymerase-1
Zn2+ impairs astrocyte glutamate uptake in a dose- and time-dependent manner. Astrocytes were exposed for 30 min to Zn2+ at the designated concentrations, and glutamate uptake was assessed immediately (zero hours), one hour, or three hours after zinc removal. Data points are means of three to four independent experiments (n = 3-4), each with measurements from two to three culture wells. *P< 0.05 versus control at the designated time point.