Figure 1

Identification of 12 CFS-associated genes in patients with CFS. The expressions of 1,072 genes were compared between 11 patients with CFS and age- and sex-matched healthy controls, and 12 common genes were identified that were significantly changed in CFS patients according to the paired t test using the cyber-T stats program (Bonferroni wide false positive rate = 0.05). Heatmap values represent the relative ratios of gene expressions between CFS and age- and sex-matched healthy controls. Hierarchical clustering was performed by the results of average linkage and distance metric of cosine θ. Gene symbols, P values, GenBank accession numbers, and names of the 12 genes are listed. P values are based on paired t tests. Patient’s numbers indicated at the bottom of column are corresponding to the numbers in Table 1.