Table 1 Clinical features of patients
From: Identification of Marker Genes for Differential Diagnosis of Chronic Fatigue Syndrome
Patient Number | Age | Gender | Duration of illness (years) | Clinical diagnosis | Symptoms according to the revised CDC criteria for CFS | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Unexplained fatigue | Impairment in memory | Sore throat | Tender nodes | Muscle pain | Multijoint pain | Headaches | Un-refreshing sleep | Post-exertional malaise | |||||
1 | 41 | F | 12 | CFS | + | + | − | − | − | + | + | + | + |
2 | 25 | M | 2 | CFS + Adjustment disorder | + | + | − | − | − | − | + | + | + |
3 | 35 | M | 3 | CFS | + | − | − | + | − | + | + | + | + |
4 | 30 | F | 5 | CFS | + | + | + | + | + | + | + | + | + |
5 | 27 | F | 1 | CFS | + | + | − | − | + | + | + | + | + |
6 | 25 | F | 7 | CFS + Mood disorder | + | + | + | − | − | + | + | + | + |
7 | 26 | F | 3 | CFS | + | + | − | − | + | + | + | + | + |
8 | 46 | F | 13 | CFS | + | + | − | − | − | + | + | + | + |
9 | 29 | M | 2 | CFS + Mood disorder | + | + | − | + | − | − | + | + | + |
10 | 30 | M | 1 | CFS | + | + | − | − | + | − | + | − | + |
11 | 53 | F | 5 | CFS | + | + | − | + | − | − | + | + | + |
Additionally enrolled patients for microarray analysis | |||||||||||||
12 | 28 | F | 2 | CFS + Adjustment disorder | + | + | Â | + | Â | Â | + | + | Â |
13 | 24 | F | 8 | CFS | + | + | + | + |  |  | − | + | + |
14 | 25 | M | 5 | CFS + Mood disorder | + | + | + | − | + | + | − | + | + |
15 | 30 | F | 3 | Mood disorder | + | + | + | − | + | + | + | + | + |
16 | 24 | F | 3 | Somatoform disorder | + | − | + | + | − | + | − | + | − |
17 | 45 | F | 12 | Personality disorder | + | + | − | − | − | − | − | − | + |
18 | 38 | F | 3 | Mood disorder | + | − | − | − | − | + | + | + | − |
19 | 39 | F | 1 | Adjustment disorder | + | + | + | − | + | + | + | + | − |
20 | 25 | F | 0.5 | Eosinophillia | + | − | − | + | + | + | + | + | − |
21 | 42 | M | 13 | Diabetes mellitus type II + hyper-CK-emia | + | Â | Â | + | Â | Â | Â | + | Â |
22 | 34 | M | 0.5 | Mood disorder | + | + | − | − | + | − | − | + | + |
23 | 15 | M | 1 | Sleep disorder | + | + | − | + | − | − | − | + | + |
24 | 42 | F | 8 | Mood disorder | + | + | − | + | − | + | + | + | − |
25 | 35 | F | 5 | Anxiety disorder | + | + | − | − | − | − | + | + | − |
26 | 60 | F | 5 | Mood disorder | + | − | + | − | − | + | + | + | − |
27 | 23 | F | 1 | Mood disorder | + | + | + | − | − | + | + | + | − |
28 | 41 | F | 2 | Mood disorder | + | − | − | + | + | − | − | + | − |
29 | 30 | M | 4 | Adjustment disorder | + | + | + | − | + | − | + | + | + |
30 | 17 | F | 1 | Adjustment disorder | + | − | + | − | + | + | + | − | − |
31 | 46 | M | 7 | Unexplained fatigue | + | + | + | − | + | + | + | − | + |
32 | 31 | F | 4 | Unexplained fatigue | + | + | + | + | + | − | + | + | + |
33 | 23 | F | 0.5 | Unexplained fatigue | + | − | + | + | − | − | − | + | + |
34 | 33 | M | 3 | Adjustment disorder | + | + | − | − | − | − | + | + | + |
Additionally enrolled patients for quantitative real-time PCR | |||||||||||||
35 | 45 | F | 0.5 | CFS | + | + | + | + | + | + | + | + | + |
36 | 13 | F | 0.75 | CFS + Adjustment disorder | + | + | + | − | + | + | + | + | + |
37 | 28 | F | 7 | CFS + Adjustment disorder | + | + | + | − | + | − | − | + | + |
38 | 31 | F | 2.5 | CFS | + | − | + | + | + | + | + | + | + |
39 | 24 | F | 4 | CFS | + | − | + | + | + | + | + | + | + |
40 | 25 | M | 2 | CFS + Adjustment disorder | + | + | + | − | + | − | + | + | + |
41 | 25 | F | 3 | CFS + Adjustment disorder | + | + | + | − | + | − | + | + | + |
42 | 35 | M | 10 | CFS | + | + | + | − | + | + | + | + | + |
43 | 27 | F | 10 | CFS | + | + | − | − | + | + | + | + | + |
44 | 29 | M | 3 | CFS | + | + | + | − | − | − | + | + | + |
45 | 41 | F | 15 | CFS | + | + | + | − | − | + | + | + | + |
46 | 45 | M | 7 | CFS | + | + | + | + | + | + | + | + | + |
47 | 46 | F | 0.8 | CFS + Secondary depression | + | + | + | − | + | − | + | − | − |
48 | 35 | M | 1.1 | CFS + Major depression | + | + | Â | + | Â | + | Â | + | + |
49 | 53 | M | 6 | CFS | + | + | + | − |  | + |  | + | + |
50 | 26 | M | 4 | CFS + Secondary depression | + | + | + | − | + | + | + | + | + |
51 | 38 | M | 6 | CFS | + | + | + | − | − | − | + | + | + |
52 | 26 | F | 1 | CFS | + | + | + | + | + | + | + | + | + |
53 | 37 | F | 1 | Major depression | + | + | − | − | + | + | − | + | + |
54 | 48 | F | 1.5 | Adjustment disorder | + | + | + | − | + − | + | − | + | + |
55 | 31 | F | 5 | Adjustment disorder | + | − | − | − | − | + | + | − | + |
56 | 28 | M | 5 | Major depression | + | + | + | − | + | + | + | + | + |
57 | 26 | M | 2 | Unexplained fatigue | + | + | − | − | − | − | − | + | + |
58 | 72 | F | 5 | Unexplained fatigue | + | + | − | − | + | + | + | + | + |
59 | 41 | F | 4 | Adjustment disorder | + | + | + | + | − | + | + | + | + |
60 | 38 | F | 9 | Adjustment disorder | + | − | − | − | + | − | + | − | + |
61 | 33 | F | 7 | Adjustment disorder | + | + | − | − | − | − | + | + | + |
62 | 32 | M | 2.5 | Hypo-cerebrospinal fluid | + | − | − | − | + | − | − | + | + |
63 | 28 | F | 4 | Mood disorder | + | + | − | − | − | + | + | + | + |
64 | 37 | M | 1 | Major depression + Sleep apnea | + | + | Â | Â | + | Â | Â | + | + |