Figure 7

Low plasma esRAGE level is a predictor of cardiovascular mortality in patients with ESRD. Cumulative mortalities in subjects with the lowest, middle, and highest tertiles of plasma esRAGE levels were estimated by Kaplan Meier analysis and the logrank test. Cardiovascular mortality in the lowest tertile of plasma esRAGE levels was significantly higher both in all subjects (A: P = .0028, n = 206) and in nondiabetic ESRD subjects (B: P = .0130, n = 171). In contrast, noncardiovascular mortality was not statistically different in all subjects (C: P = .89, n = 206) and in nondiabetic subjects (P = .91, n = 171). Modified from (62).