Figure 8

Correlation between plasma esRAGE and AGEs, pentosidine (A) and carboxymethyllysine (CML) (B). In all subjects, correlation between plasma esRAGE and both pentosidine (r = 0.616) and CML (r = 0.492) were significant (P< 0.001). Plasma pentosidine level was also significantly correlated with plasma esRAGE level in the two subpopulation of nonhemodialysis (open circle: r = 0.160, P= .005, n = 308) and hemodialysis subjects (closed circle: r = 0.216, P= .002, n = 206). In contrast, plasma CML level did not show significant correlation with plasma esRAGE level in the two subgroups of nonhemodialysis (open circle: r = 0.105, ns, n = 293) and hemodialysis subjects (closed circle: r = −0.030, ns, n = 204). Spearman’s rank correlation test was used for analyses.