Figure 2
From: The Pathogenesis of Lyme Neuroborreliosis: From Infection to Inflammation
The inflammatory B-cell response in the CSF in response to the CNS infection. Borrelia are recognized by monocytic cells (1), which produce the B-cell-attracting chemokine CXCL13 (2). B cells immigrate into the CSF (3) and mature to plasma cells (4). These plasma cells can produce B.b.-specific antibodies (5) that can eventually destroy the invaded spirochetes (6).