|  | p16 hypermethylation status |  | |
---|---|---|---|---|
Parameter | All | negative | positive | P |
Gender, n (%) | Â | Â | Â | Â |
Female | 80 (44.2) | 52 (65.0) | 28 (35.0) | Â |
Male | 101 (55.8) | 64 (63.4) | 37 (36.6) | 0.88a |
Mean age (year ± SD) | 69 ± 14 | 68 ± 14 | 72 ± 12 | 0.029b |
Tumor location,d n (%) | Â | Â | Â | Â |
Right-sided colon | 62 (34.4) | 37 (58.7) | 26 (41.3) | Â |
Left-sided colon | 47 (26.1) | 34 (72.3) | 13 (27.7) | Â |
Rectum | 71 (39.5) | 45 (63.4) | 26 (36.6) | 0.33c |
Differentiation grade, n (%) | Â | Â | Â | Â |
High/Moderate | 119 (65.7) | 79 (66.4) | 40 (33.6) | Â |
Low | 62 (34.3) | 37 (59.7) | 25 (40.3) | 0.42a |
Dukes’ tumor stage, n (%) |  |  |  |  |
A | 10 (5.5) | 7 (70.0) | 3 (30.0) | Â |
B | 71 (39.2) | 42 (59.2) | 29 (40.8) | Â |
C | 53 (29.3) | 38 (71.7) | 15 (28.3) | Â |
D | 47 (26.0) | 29 (61.7) | 18 (38.3) | 0.50c |
Total, n (%) | 181 (100) | 116 (64.1) | 65 (35.9) | Â |