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Table 3 Mean gene expression levels in colorectal mucosa of Dukes’ A–D patients stratified by p16 hypermethylation status.

From: p16INK4a Gene Promoter Hypermethylation in Mucosa as a Prognostic Factor for Patients with Colorectal Cancer

   

p16 hypermethylation

 

Gene

n a

All

n

Negative

n

Positive

P b

RFC-1

60

0.14 ± 0.17

36

0.15 ± 0.20

24

0.13 ± 0.12

0.89

FPGS

63

0.84 ± 0.61

38

0.92 ± 0.60

25

0.72 ± 0.61

0.079

TS

62

2.6 ± 2.6

37

2.2 ± 2.1

25

3.2 ± 3.2

0.29

  1. aEnough material for gene expression analysis could only be obtained for the number of patients specified in the table.
  2. bP by Kruskal-Wallis’ test.