From: p16INK4a Gene Promoter Hypermethylation in Mucosa as a Prognostic Factor for Patients with Colorectal Cancer
p16 hypermethylation
Gene
n a
All
n
Negative
Positive
P b
RFC-1
60
0.14 ± 0.17
36
0.15 ± 0.20
24
0.13 ± 0.12
0.89
FPGS
63
0.84 ± 0.61
38
0.92 ± 0.60
25
0.72 ± 0.61
0.079
TS
62
2.6 ± 2.6
37
2.2 ± 2.1
3.2 ± 3.2
0.29