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Table 4 Correlation between RFC-1, FPGS, and TS gene expression in colorectal mucosa of Dukes’ A–D patients stratified by p16 hypermethylation status.

From: p16INK4a Gene Promoter Hypermethylation in Mucosa as a Prognostic Factor for Patients with Colorectal Cancer

 

RFC-1 and FPGS

FPGS and TS

 

n a

r b

P c

n a

r b

P c

All

60

0.41

0.0013

62

0.57

< 0.0001

p16 hypermethylation

      

Negative

36

0.57

0.0003

37

0.57

0.0003

Positive

24

−0.0001

1.0

25

0.68

0.0002

  1. aEnough material for gene expression analysis could only be obtained for the number of patients that is specified in the table.
  2. br = correlation coefficient.
  3. cP by Pearson.
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Molecular Medicine

ISSN: 1528-3658