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Figure 1 | Molecular Medicine

Figure 1

From: Lysophosphatidic Acid Inhibits Bacterial Endotoxin-Induced Pro-Inflammatory Response: Potential Anti-Inflammatory Signaling Pathways

Figure 1

Effect of LPA on mice survival to endotoxemia. 30 male CD-1 mice were separated into two groups randomly. Fifteen mice in Group 1 were injected intravenously with LPA (10 mg/kg) followed by intraperitoneal injection of LPS (75 mg/kg). Fifteen mice in Group 2 were injected with PBS instead of LPA. Mouse survival was monitored every 24 h. Statistics were determined with Gehan-Breslow-Wilcoxon Test using GraphPad Prism software. LPA injected mice exhibited significantly enhanced survival to LPS challenge (P < 0.05).

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Molecular Medicine

ISSN: 1528-3658