Figure 2

Chi-square test (χ²) statistics from the 2-by-2 allele count table of 744 case-control samples matched 1:1 by DRB1 genotype (372 cases and 372 controls). Association signals are separated into two types: a) positive associations (8.1 allele frequency is greater in RA cases than controls) (+ symbol), and b) negative associations (8.1 allele frequency is greater in controls than in cases) (− symbol).