Skip to main content

Table 2 a Comparison of Odds Ratios among DR4 subgroups for the MHC region between ~29 and ~29.4 Mb.

From: Several Regions in the Major Histocompatibility Complex Confer Risk for Anti-CCP-Antibody Positive Rheumatoid Arthritis, Independent of the DRB1 Locus

   

SE(a)/X or SE(a)/SE(a) (n = 502)

0404/X but not 0401 (n = 106)

0401/X but not 0404 (n = 276)

Marker

position

Gene

OR

OR (95%CI)

OR

OR (95% CI)

OR

OR 95% CI

rs3763338

29002291

RFP

0.58

(0.37–0.93)

0.34

(0.10–1.10)

0.55

(0.97–3.47)

rs2071788

29020287

RFP

0.63

(0.39–1.02)

0.34

(0.10–1.10)

0.54

(0.91–3.71)

rs6923005

29084051

ZNF311

0.70

(0.53–0.92)

0.69

(0.36–1.31)

0.82

(0.84–1.77)

rs6930903

29089224

ZNF311

0.70

(0.53–0.92)

0.69

(0.36–1.31)

0.82

(0.84–1.77)

rs6456889

29118804

OR2W1

0.72

(0.54–0.95)

0.72

(0.37–1.38)

0.83

(0.82–1.76)

rs9295794

29212915

OR2J3

0.62

(0.39–1.01)

0.34

(0.10–1.10)

0.57

(0.87–3.58)

rs9357078

29405646

OR5U1

0.58

(0.38–0.89)

0.18

(0.05–0.63)

0.59

(0.96–3.02)

rs9380120

29443517

OR12D3

0.60

(0.39–0.91)

0.24

(0.08–0.74)

0.59

(0.96–3.02)

  1. aAs in Table 1, the ORs are shown with respect to the 8.1 haplotype associated allele for each marker. Markers that show substantially increased and significant evidence of association in the DRB1*0404 subset are shown in bold.
Back to article page

Molecular Medicine

ISSN: 1528-3658