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Figure 7 | Molecular Medicine

Figure 7

From: 1,2-Dioleoyl-3-Trimethylammonium-Propane (DOTAP)-Formulated, Immune-Stimulatory Vascular Endothelial Growth Factor A Small Interfering RNA (siRNA) Increases Antitumoral Efficacy in Murine Orthotopic Hepatocellular Carcinoma with Liver Fibrosis

Figure 7

A simplified overview elucidating our hypothesis: siRNA uptake is improved by efficacy due to formulation with DOTAP, whereas naked VEGF-A siRNA treatment results in low uptake, inducing only limited gene knockdown and low antitumoral efficacy.

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Molecular Medicine

ISSN: 1528-3658