Figure 2From: No Longer an Innocent Bystander: Epithelial Toll-Like Receptor Signaling in the Development of Mucosal InflammationTLR4 signaling pathways. LPS binding to TLR4 requires binding protein (LBP), MD-2, and the co-receptor CD-14 which initiates MyD88-dependent (blue) and MyD88-independent (yellow) signaling pathways. See text for details.Back to article page