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Figure 3 | Molecular Medicine

Figure 3

From: No Longer an Innocent Bystander: Epithelial Toll-Like Receptor Signaling in the Development of Mucosal Inflammation

Figure 3

A model of TLR-mediated inflammation in the mucosa. (A) During basal conditions, TLR signaling is required for mucosal homeostasis. (B) Under conditions of physiological stress, TLR signaling in epithelial cells becomes exaggerated in part through increased TLR expression. This leads to an impairment in epithelial function, increased injury, and decreased repair, resulting in mucosal inflammation.

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Molecular Medicine

ISSN: 1528-3658