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Table 1 Toll-like receptors and their known ligands

From: No Longer an Innocent Bystander: Epithelial Toll-Like Receptor Signaling in the Development of Mucosal Inflammation

TLR

Ligand(s)

1

Triacyl lipoproteins (126)

2

Lipoproteins (127)

 

Peptidoglycan (128,129)

 

Lipoteichoic acid (128)

 

Zymosan (130,131)

 

Heat shock proteins (132,133)

3

Double stranded RNA (134)

4

LPS (37,135)

 

Taxol (136) Heat shock proteins (132,137,138)

 

Fibronectin (139)

 

Hyaluronic Acid (140)

 

Heparan Sulfate (141)

 

Fibrinogen (142)

 

Respiratory Syncytial Virus Fusion Protein (106)

 

Murine Retroviral Envelope Protein (143)

5

Flagellin (58)

6

Diacyl Lipopeptides (144)

 

Lipoteichoic acid (131)

 

Zymosan (131)

7

Single-stranded RNA (145,146)

 

Imidazoquinoline (59)

8

Single-stranded RNA (146)

 

Imidazoquinoline (147)

9

Bacterial (demethylated CpG) DNA (148)

10

Unknown

11

Profilin (149)

 

Uropathogenic Bacteria (114)