Skip to main content

Table 2 A summary of known damage associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs)

From: No Longer an Innocent Bystander: Epithelial Toll-Like Receptor Signaling in the Development of Mucosal Inflammation

Endogenous Signals (DAMPs)

Exogenous Signals (PAMPs)

Heat shock proteins (Hsp60, Hsp70, Gp96) (132,133,138)

Proteoglycan (128,129)

Fibrinogen (142)

Lipoteichoic acid (128)

Surfactant Protein-A (150)

Lipoproteins (126,127,144)

Fibronectin extra domain A (139)

Zymosan (130,131)

Heparan Sulfate (141)

Microbial Hsp (132,137,138)

Soluble Hyaluronan (140)

Viral ds RNA, ss RNA, synthetic poly I:C (134,145,146)

β-defensin 2 (151)

Lipopolysaccharide (LPS) (135,152)

High mobility group box 1 protein (HMGB1) (153)

Plant derivatives (Taxol) (136)

Messenger RNA (mRNA) (154)

Viral proteins (106,143)

Self DNA (155)

Flagellin (58)

Uric Acid (156)

Bacterial DNA (148)

Profilin (149)