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Figure 4 | Molecular Medicine

Figure 4

From: Immune Dysregulation and Tumor-Associated Gene Changes in Recurrent Respiratory Papillomatosis: A Paired Microarray Analysis

Figure 4

Ingenuity pathway analysis. Multiple pathway interactions showing both direct (solid line) and indirect (dashed line) associations between multiple dysregulated genes, having a fold change greater than 3.0, including: VEGF, NFKB, PLAT, and various chemokines (4A) having a significance score of 51, and MAPK, PI3K, AkT, Ap1, Pkc, and HIF1α, and IL8 (4B) having a significance score of 28. This analysis was performed on the 109 genes listed in Supplementary Table 5. Square: cytokine/growth factor; vertical diamond: enzyme; horizontal diamond: peptidase; circle: other; parallelogram: transporter; circle-in-circle: complex; oval: trans-membrane receptor; shaded circle-in-circle: group.

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Molecular Medicine

ISSN: 1528-3658