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Figure 2 | Molecular Medicine

Figure 2

From: Surface Expression of Bcl-2 in Chronic Lymphocytic Leukemia and Other B-Cell Leukemias and Lymphomas Without a Breakpoint t(14;18)

Figure 2

Flow cytometric analysis of Bcl-2 surface membrane expression. (A) Bcl-2 levels on fresh B cells. Graphic representation of the percent of smBcl-2+ cells in B cells isolated from age-matched normal individuals, CD5− and CD5+ fractions enriched from cord blood B cells, M-CLL and U-CLL patients, and a composite of the B-CLL patients were compared after flow cytometric staining with the PE-conjugated mouse anti-human Bcl-2 mAb 100. (B) Population analysis of smBcl-2+ cells. Contour plot of Bcl-2 levels in B cells from age-matched healthy controls and B-CLL patients. Normal controls are pictured as CD19 (y-axis) by Bcl2 (x-axis). B-CLL samples are first gated on CD19 and then shown as CD5 (y-axis) by Bcl2 (x-axis).

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Molecular Medicine

ISSN: 1528-3658