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Figure 3 | Molecular Medicine

Figure 3

From: Surface Expression of Bcl-2 in Chronic Lymphocytic Leukemia and Other B-Cell Leukemias and Lymphomas Without a Breakpoint t(14;18)

Figure 3

Patterns of smBcl-2 expression. (A) Analysis of smBcl-2 levels on frozen cells. Graphic representation of Bcl-2 levels in B cells from age-matched healthy subjects (first bar on left), M-CLL patients (second bar), and all B-CLL patients combined (right bar). Data were analyzed with Student ttest. A significant difference was found between B-CLL patients and normal control subjects (P < 0.03). (B) Analysis of gated cell populations. Two B-CLL samples were analyzed after gating into subpopulations based on forward and side scatter (left column), ungated (second column) R2 cells only (third column), or R1 cells only (fourth column). Numbers represent the R1 and R2 populations in the left graph and percent double positive cells, CD19 (y-axis) and Bcl2 (x-axis), in the remaining.

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Molecular Medicine

ISSN: 1528-3658