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Figure 4 | Molecular Medicine

Figure 4

From: Reversing Established Sepsis in Rats with Human Vasoactive Hormone Adrenomedullin and its Binding Protein

Figure 4

Alterations in intestinal mucosal permeability (A) to fluorescein isothio-cyanate dextran with a molecular weight of 4000 Da (FD4) and bacterial translocation to mesenteric lymph nodes (B) in sham-operated animals (Sham) and septic animals treated with human albumin (Vehicle) or human adrenomedullin (AM)/human adrenomedullin binding protein (AMBP)-1 (24/80 µg/kg BW) at 20 h after cecal ligation and puncture (CLP). Data are presented as means ± SE (n = 4–8/group) and compared by one-way analysis of variance and Student-Newman-Keuls test: *P < 0.05 versus sham group; #P < 0.05 versus vehicle group.

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