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Table 2 Quit success genes.a

From: Genome-Wide Association for Nicotine Dependence and Smoking Cessation Success in NIH Research Volunteers

Gene

Gene description

Chromosome

Base pair

Clustered SNPs

A2BP1

Ataxin 2-binding protein 1

16

6009133

3

CSMD1

CUB and Sushi multiple domains 1

8

2782789

10

DSCAM

Down syndrome cell adhesion molecule

21

40306213

3

PCDH15

Protocadherin 15

10

55250866

3

RARB

Retinoic acid receptor β

3

25444758

3

  1. aGenes that contain overlapping clusters of nominally positive SNPs in comparisons of nicotine-dependent individuals who reported continuing smoking when interviewed versus those who reported prolonged abstinence and clusters of nominally positive SNPs from studies of at least two samples of successful versus unsuccessful quitters in clinical trials recently reported by Uhl et al. (14). Columns list gene description, chromosome, base pairs for gene’s start, and number of nominally positive SNPs that lay in clusters within the gene’s exons and in 10-kb genomic flanking regions in the current dataset. All genes identified by clustered, nominally positive data from the current dataset are presented in Table S2.