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Table 1 Increased MIF expression correlates with tumor differentiation, regional lymph node status, and liver metastasis.

From: Macrophage Migration Inhibitory Factor Promotes Colorectal Cancer

MIF staining scorea

1

2

3

P value

Sex

    

Male

13

11

3

 

Female

8

9

5

0.498

Stage

    

I

4

2

1

 

II

4

4

1

 

III

3

4

3

 

IV

10

10

3

0.866

Differentiation

    

Well

8

1

0

 

Moderate

10

14

4

 

Poor

3

5

4

0.018

Regional lymph nodes

    

N0

6

9

7

 

Nx

15

11

1

 

N1

5

15

0

 

N2

1

8

3

 

N3

0

0

4

0.017

Liver metastasis

    

Yes

7

8

7

 

No

14

12

1

0.027

Morphology

    

Polypoid exophytic

5

2

4

 

Diffuse infiltrative

3

6

0

 

Ulcerative

7

9

4

 

Fungating

6

3

0

0.140

  1. aMIF staining was scored on a scale of 1 (weakly positive) to 3 (strongly positive).
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Molecular Medicine

ISSN: 1528-3658