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Table 3 Significant predictors of CVD in a multinomial logistic regression CKD 3–5 patients.

From: Elevated Serum Macrophage Migration Inhibitory Factor (MIF) Concentrations in Chronic Kidney Disease (CKD) Are Associated with Markers of Oxidative Stress and Endothelial Activation

  

95% Cl

 

Parameter

Odds ratio

Lower

Upper

P value

Intercept of CVD

   

<0.0001

Diabetes mellitus, presence

2.35

1.26

4.39

0.007

Sex, men

2.21

1.16

4.22

0.01

Age, 50–65 years

4.61

1.97

10.79

0.0004

Age, > 65 years

10.60

4.41

25.48

<0.0001

Non inflamed and high MIF

0.83

0.33

2.06

0.7

Inflamed and low MIF

2.11

0.89

4.99

0.09

Inflamed and high MIF

2.39

1.02

5.63

0.04

  1. The model included CVD as the dependent variable and all factors significantly associated with the dependent variable in univariate analysis. Inflamed patients were defined as those with IL-6 >4.3 pg/mL (median), and high MIF was defined as those with >676 pg/mL (median); Pseudo r2 = 0.22; P < 0.001; ages 20–49. Non-inflamed patients with low MIF were considered reference groups.
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Molecular Medicine

ISSN: 1528-3658