Figure 2

Expression levels of Nrf2-modulated genes in small airway epithelium. A list of murine Nrf2-modulated genes was compiled and used to identify the human homologs. The gene expression in small airway epithelium was examined to generate a list of putative human Nrf2-modulated genes that are highly responsive to smoking (Supplemental Table 1). Shown is the normalized expression level for each individual (38 healthy nonsmokers (○), 45 healthy smokers (●)). The gene names and the P values are located on the abscissa, the relative gene expression levels are on the ordinate as a log scale.