Figure 8

(A) Moderately differentiated colorectal cancer with an area with grade 3 SV-1 immunohistochemical expression (arrow) and an area with grade 2 SV-1 immunohistochemical expression (arrowhead); (B) moderately differentiated colorectal cancer with an area with grade 2 SV-1 immunohistochemical expression (arrow) and an area with grade 1 SV-1 immunohistochemical expression (arrowhead); (C) normal colon mucosa with supranuclear SV-1 immunohistochemical expression (arrow) and adjacent low-differentiated colorectal cancer with no SV-1 immunohistochemical expression (arrowhead); (D) low-differentiated colorectal cancer with pericolic fat invasion and with small foci with grade 2 (arrow) and grade 1 (arrowhead) SV-1 immunohistochemical expression (All magnifications 400×, except C 100×) 118 × 88 mm (300 × 300 DPI).