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Table 1 Genotype frequencies of xenobiotic metabolizing genes.

From: Analysis Association between Mitochondrial Genome Instability and Xenobiotic Metabolizing Genes in Human Breast Cancer

 

Frequency

 

Gene and genotype

Cases,a

n (%)

Reportedb

Reference

GSTM-1

94

   

 null/null

38 (40.4)

42–60

(20,29,32,39)

 +∫+/null

56 (59.6)

40–58

 

GSTT-1

94

   

 null/null

17 (18)

16–21.5

(29,32)

 +∫+/null

77 (82)

78.5–84

 

NAT-2

94

   

 Rapid

7 (7.4)

52 (55.3)

36.8–60.1

(20,40)

 Intermediate

45 (47.9)

  

 Slow

42 (44.7)

39.9–63.2

 
  1. aFrequency found in nontumoral samples with n number of case studied for each gene.
  2. bAverage frequency and standard deviations estimated according to the data published by other groups (bibliographic reference), in normal subjects of similar ethnicity (since it works with the average, the sum of the averages of the two genotypes of a particular gene may be less than 100).