Table 2 Genotype analysis association with mtGI and metabolizing genes.
mtGI | ||||
|---|---|---|---|---|
Gene and Genotype | Absence, n(%) | Presence, n(%) | Odds ratio (95% CI) | P value |
GSTM-1 | 59 | 35 | ||
+a | 42 (71.2) | 14 (40) | 1 (reference) | |
null | 17 (28.8) | 21 (60) | 3.71 (1.41–9.88) | 0.006b |
GSTT-1 | 62 | 32 | ||
+ | 50 (80.6) | 27 (84.4) | 1 (reference) | |
null | 12 (19.4) | 5 (15.6) | 0.77 (0.21–2.71) | 0.87c |
NAT-2 | 62 | 32 | ||
R∫I | 30 (48.4) | 22 (68.8) | 1 (reference) | |
S | 32 (51.6) | 10 (31.2) | 0.43 (0.16–1.14) | 0.09d |