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Figure 1 | Molecular Medicine

Figure 1

From: Progesterone with Vitamin D Affords Better Neuroprotection against Excitotoxicity in Cultured Cortical Neurons than Progesterone Alone

Figure 1

Effect of PROG on glutamate-induced LDH release (A) and MTT reduction (B) in rat primary cortical neurons. Primary cells were pretreated with different concentrations of PROG for 24 h and subsequently exposed to glutamate (0.5 µmol/L) for 24 h. PROG was present in the culture medium during the glutamate exposure. The values are expressed as mean ± SEM of four experiments. Significant difference: #P < 0.001 compared with control; *P < 0.001 compared with vehicle.

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