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Figure 4 | Molecular Medicine

Figure 4

From: Progesterone with Vitamin D Affords Better Neuroprotection against Excitotoxicity in Cultured Cortical Neurons than Progesterone Alone

Figure 4

Effect of combinatorial treatment of PROG and VDH on glutamate-induced LDH release (A) and MTT reduction (B) in rat primary cortical neurons. Primary cells were pretreated with different combinations of PROG and VDH for 24 h and subsequently exposed to glutamate (0.5 µmol/L) for 24 h. Drugs were present in the culture medium during the glutamate exposure. The values are expressed as mean ± SEM of four experiments. Significant difference: #P < 0.001 compared with control, *P < 0.001 compared with vehicle, and §P < 0.01 compared with P20 group.

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Molecular Medicine

ISSN: 1528-3658