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Table 2 Comparison of association of outcome with patient scores.

From: A Genomic Score Prognostic of Outcome in Trauma Patients

 

DFR score

APACHE II score

Injury Severity Score

Outcomea

   

Days in ICU

2.9± 0.9 (0.001)

2.9±0.9 (0.001)

3.3±0.9 (< 0.001)

Days on ventilator

3.0±0.6 (< 0.001)

2.9±0.7 (< 0.001)

2.1± 0.7 (0.002)

Hospital length of stay

4.4± 1.4 (0.002)

3.8± 1.4 (0.009)

3.5± 1.4 (0.02)

Maximum Marshall score

1.1±0.2 (< 0.001)

1.1±0.2 (< 0.001)

0.8±0.2 (< 0.001)

Maximum Denver score

0.7± 0.2 (< 0.001)

0.6±0.2 (< 0.001)

0.4± 0.2 (0.005)

Eventb

   

Mortality

1.9 (0.9,3.6) (0.08)

2.4 (1.0,5.8) (0.06)

1.9 (0.9,4.1) (0.08)

MODS (Marshall criterion)

1.6 (1.1,2.2) (0.008)

1.8 (1.3,2.6) (0.001)

1.6 (1.1,2.2) (0.006)

MODS (Denver criterion)

2.1 (1.4,3.3) (< 0.001)

1.8 (1.1,3.0) (0.02)

1.5 (1.0, 2.4) (0.05)

Nosocomial Infections

1.6 (1.2,2.3) (0.006)

2.0 (1.4,2.9) (< 0.001)

1.7 (1.2,2.4) (0.002)

Surgical Site Infections

1.4 (1.0,2.0) (0.08)

1.8 (1.2,2.8) (0.009)

1.3 (0.9, 1.8) (0.24)

  1. aThe model is Outcome = Intercept + α Score + ε. Each table entry shows the estimated regression coefficient α, its standard error, and its significance. Standardized scores were used in these models. The means and standard deviations used to standardize patient scores were: DFR 13.39 (0.68), APACHE 27.25 (6.01), ISS 31.13 (13.46).
  2. bFor event outcomes, the model is Log Odds (Event) = Intercept + α Score. Each table entry shows the estimated odds ratio, its 95% CI, and its significance. The odds ratio is exp (α); it indicates the increased (or decreased) odds of the event for one unit increase in the standardized score.
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Molecular Medicine

ISSN: 1528-3658