Differentiation of Bone Marrow-Derived Endothelial Progenitor Cells Is Shifted into a Proinflammatory Phenotype by Hyperglycemia

Table 1 Mouse characteristics.^a

	C57BL/6J Control	C57BL/6J STZ	FVB/N Control	FVB/N STZ
n	18	26	17	23
Blood glucose, mmol/L	6.7 ± 2.0	24.1 ± 5.5^b	9.1 ± 1.8	27.8 ±4.5^b
HbA_1c,%	3.9 ± 0.2	7.6 ±0.7^b	4.1 ± 0.5	5.9 ±0.5^b
Weight, g	28.5 ± 2.2	20.0 ± 1.2^b	30.5 ± 2.3	22.5 ± 2.9^b
Bone marrow, cells × 10⁸	0.8 ± 0.3	0.8 ±0.2	0.7 ±0.2	0.9 ±0.3

^aParameters were measured after 6 wks of STZ-induced hyperglycemia or in littermate control mice matched for age and sex that were injected with buffer. Values represent mean ± SD.
^bP < 0.05 versus buffer.

ISSN: 1528-3658