Table 1 Baseline characteristics of the study population by subsequent diagnostic categories.
Characteristics | Cognitively normal (n = 179) | MCI/AD (n = 24) |
|---|---|---|
n (%) | ||
Female | 91 (50.8) | 7 (29.2)a |
White | 175 (97.8) | 24 (100.0) |
Statin use | 72 (40.2) | 9 (37.5) |
Antihypertensive use | 72 (40.2) | 7 (29.2) |
APOE ε4+ | 56 (31.3) | 10 (41.7) |
Placebo | 79 (44.1) | 7 (29.2) |
Celecoxib | 48 (26.8) | 7 (29.2) |
Naproxen | 52 (29.1) | 10 (41.7) |
Mean ± SD | ||
Age, years | 76.61 ± 3.9 | 78.21 ± 3.9 |
Education, years | 14.77 ± 2.8 | 14.77 ± 3.2 |
Mini Mental Status Exam score | 28.91 ± 1.3 | 28.50 ± 1.3 |
Systolic blood pressure, mm Hg | 133.02 ± 11.5 | 135.07 ± 11.7 |
Serum creatinine, mg/dLb | 0.94 ± 0.2 | 0.93 ± 0.2 |
Total cholesterol, mg/dLb | 168.50 ± 85.0 | 162.67 ± 114.5 |
Triglycerides, mg/dL | 194.31 ± 39.9 | 186.58 ± 35.9 |
Serum Aβ1–40, pg/mL | 146.94 ± 55.6 | 136.22 ± 42.1 |
Median (interquartile range) | ||
Serum Aβ1–42, pg/mL | 13.06 (6.35–23.46) | 6.33 (1.92–21.08)a |
Serum A β 1–42 /A β 1–40 | 0.09 (0.04–0.15) | 0.05 (0.02–0.13)a |