Skip to main content
Figure 2 | Molecular Medicine

Figure 2

From: RNA Recognition Motif (RRM) of La/SSB: The Bridge for Interparticle Spreading of Autoimmune Response to U1-RNP

Figure 2

Immunization of rabbits with the epitope 145–164 aa of La/SSB. (A) Reactivity against pep145–164 and control peptide at different postimmunization time points. (B) Reactivity against La/SSB and U1-RNP antigens as assessed by specific ELISA assays. The development of anti-La/SSB antibodies (at wk 3) preceded the production of anti-U1-RNP antibodies (wk 7–20). (C) Western blot (using rabbit thymus extract) showing the development and the attenuation of anti-70kD activity of rabbit sera after immunization with pep145–164.

Back to article page

Molecular Medicine

ISSN: 1528-3658