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Figure 2 | Molecular Medicine

Figure 2

From: Human Neutrophil Elastase-Mediated Cleavage Sites of MMP-9 and TIMP-1: Implications to Cystic Fibrosis Proteolytic Dysfunction

Figure 2

(A) CF patients demonstrate increased HNE activity: Sputum from CF patients (n = 9) are measured for HNE activity and then normalized to normal nondisease controls (n = 5), *P < 0.05. (B) MMP-9/TIMP-1 ratio correlates with HNE concentration in CF patients: MMP-9/TIMP-1 ratio and HNE concentration demonstrates an r value of 0.81 (P < 0.05) in CF specimens (n = 9).

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Molecular Medicine

ISSN: 1528-3658