Table 1 The frequencies of the CRP −286 (C > T > A) genotypes carriers, characterization of the genotype carriers and association of the genotypes with the frequency of malaria episodes over 9 years of follow-up in Daraweesh village.
CRP genotype | Frequency (n) | Age in years in 2005 (median, 25–75%) | Sex, M/F | Proportions of Hb AS (n) | Malaria episodes (median, 25–75%) |
|---|---|---|---|---|---|
AA | 0.052 (10) | 27.0 (11.0–43.0) | 1/9 | 10.0% (1) | 1.5 (0.0–2.00) |
AC | 0.193 (37) | 24.0 (12.8–46.8) | 12/25 | 16.2% (6) | 2.0 (1.00–3.00) |
AT | 0.125 (24) | 19.5 (13.5–36.5) | 7/17 | 20.8% (5) | 2.0 (1.00–3.00) |
CC | 0.302 (58) | 21.5 (13.0–32.0) | 19/39 | 19.0% (11) | 1.0 (0.00–2.00) |
CT | 0.245 (47) | 16.0 (9.3–29.8) | 23/24 | 17.0% (8) | 1.0 (0.00–2.00) |
TT | 0.083 (16) | 17.0 (11.0–23.5) | 5/11 | 12.5% (2) | 2.0 (0.00–2.00) |
Total | (192) | 19.0 (12.0–34.5) | 67/125 | 17.2 (33) | 1.5 (0.00–2.50) |
Range | 6–78 | 0–7 | |||
P values | P = 0.382a | P = 0.964b | P= 0.076a |