Table 3 Correlations of MGMT, RARβ, RASSF1A, and CDH13 promoter methylation with inflammatory and angiogenic factors.
MGMT methylation | RARβ methylation | RASSF1A methylation | CDH13 methylation | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Presence median (range) | Absence median (range) | P | Presence median (range) | Absence median (range) | P | Presence median (range) | Absence median (range) | P | Presence median (range) | Absence median (range) | P | |
IL-6 expression, % | 64.5 (7–80) | 15 (0–30) | 0.004 | 69.5 (25–80) | 15 (0–40) | 0.002 | 75 (60–80) | 25 (0–80) | 0.0081 | 55 (25–80) | 30 (0–80) | 0.1320 |
IL-8 expression, % | 17.5 (5–70) | 10 (2–30) | 0.2892 | 25 (10–70) | 10 (2–30) | 0.2326 | 17.5 (5–40) | 15 (2–70) | 0.2326 | 25 (5–70) | 30 (2–30) | 0.1640 |
VEGF expression, % | 60 (50–80) | 50 (40–70) | 0.0679 | 65 (50–80) | 60 (40–70) | 0.0757 | 65 (5–80) | 60 (40–70) | 0.8034 | 65 (5–80) | 60 (40–70) | 0.8040 |
COX-2 expression, % | 30 (10–70) | 25 (15–40) | 0.6603 | 37.5 (10–70) | 25 (15–40) | 0.1640 | 37.5 (10–70) | 25 (15–40) | 0.2821 | 37.5(10–70) | 25 (15–40) | 0.2821 |