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Table 1 Distribution of MTHFR, MTR and MTRR genotypes in CRC patients and controls.

From: MTHFR, MTR, and MTRR Polymorphisms in Relation to p16INK4A Hypermethylation in Mucosa of Patients with Colorectal Cancer

Genotype

CRC patients, n (%)a

Controls, n (%)b

P c

MTHFR 677

   

CC

81 (46.3)

167 (55.9)

 

CT

76 (43.4)

107 (35.8)

 

TT

18 (10.3)

25 (8.4)

0.13

MTR 2756

   

AA

112 (63.6)

193 (64.8)

 

AG

55 (31.3)

92 (30.9)

 

GG

9 (5.1)

13 (4.3)

0.92

MTRR 66

   

AA

22 (12.4)

50 (16.7)

 

AG

94 (53.1)

152 (50.8)

 

GG

61 (34.5)

97 (32.4)

0.45

  1. aOf 180 patient samples, 175, 176 and 177 were informative for the MTHFR, MTR, and MTRR polymorphisms, respectively.
  2. bOf 300 control samples, 299, 298 and 299 were informative for the MTHFR, MTR and MTRR polymorphisms, respectively.
  3. cP by Pearson chi-square test.
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Molecular Medicine

ISSN: 1528-3658