From: Upregulation of SPRR3 Promotes Colorectal Tumorigenesis
 | Percentage of patients with SPRR3 expressiona |  | ||
---|---|---|---|---|
Parameters | Positive expression | P valueb | Overexpression | P valueb |
Sex, male/female | 59.4/75 | 0.045c | 25/39.1 | 0.065 |
Age, years, ≤50/>50 | 73.3/65.3 | 0.279 | 30/32.7 | 0.486 |
Stage,d I + II/III + IV | 66/68 | 0.482 | 26.4/36 | 0.171 |
Tumor characteristics | Â | Â | Â | Â |
Site, right colon/left colone | 76/65 | 0.211 | 40/30.1 | 0.235 |
Growth pattern, expanding/infiltrative | 67.9/63.2 | 0.436 | 33.9/21.1 | 0.201 |
Differentiation, well and moderately differentiated/poorly differentiated and mucinous | 67/69.2 | 0.569 | 29.6/53.8 | 0.075 |
Lymphovascular invasion, no/yes | 55.2/80.3 | 0.002c | 20.9/44.3 | 0.004c |
Either MLH1 or MSH2 expression, no/yes | 77.8/70.2 | 0.484 | 66.7/32.1 | 0.048c |