Figure 4

Exercise training reduced fibrosis in myositis muscles. Resistance exercise training resulted in a significant reduction in nonmuscle area infiltrates. (A) Gross morphological analysis via Gomori trichrome staining pre- and posttraining (fibrotic areas are indicated by arrows). (B) Quantitative analysis of tissue sections demonstrates a decrease in non-muscle area. (C) Type I collagen protein levels in pre- and posttraining biopsies in individual patients. (D) Type I collagen levels were reduced significantly after resistance training (n = 6; *P = 0.01). AU, arbitrary units. Data are means ± SEM.