Figure 3
From: Role of Hydrogen Sulfide in Severe Burn Injury-Induced Inflammation in Mice
Effect of PAG administration on liver H2S synthesizing activity (A), plasma H2S concentration (B) and lung (C) and liver (D) MPO activity 8 h after burn injury. Mice with burn injury were randomly given PAG (50 mg/kg i.p.) or saline 1 h before (PAG + burn or saline + CLP) or 1 h after (burn + PAG or burn + saline) burn injury. Eight hours after burn injury, plasma H2S concentration and H2S-synthesizing activity in liver were measured as described in Materials and Methods. Results shown are mean ± SEM (n = 9 animals/group). +P< 0.05, ++P<0.01 when PAG treated animals were compared with saline treated animals.