Figure 4

Morphological changes in lung and liver 8 h after induction of burn injury with or without PAG treatment in sections stained with hematoxylin and eosin. (A) Lung from sham group; (B) lung from mice subjected to burn injury with saline pretreatment; (C) lung from mice subjected to burn injury with PAG prophylactic treatment; (D) lung from mice subjected to burn injury with saline posttreatment; (E) lung from mice subjected to burn injury with PAG therapeutic treatment; (F) liver from sham group; (G) liver from mice subjected to burn injury with saline pretreatment; (H) liver from mice subjected to burn injury with PAG prophylactic treatment; (I) liver from mice subjected to burn injury with saline posttreatment; (J) liver from mice subjected to burn injury with PAG therapeutic treatment. The scale bar is 2 µm. Mice subjected to burn injury demonstrated alveolar thickening and severe leukocyte infiltration in the interstitium (arrowed) in the lung (B,D) and hepatocyte swelling and transmigrated neutrophils (arrow) in the liver (G,I).