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Figure 3 | Molecular Medicine

Figure 3

From: Peroxynitrite-induced Nitration of Cyclooxygenase-2 and Inducible Nitric Oxide Synthase Promotes Their Binding in Diabetic Angiopathy

Figure 3

Colocalization of COX-2 and iNOS in the rat aorta and glomerulus. The colocalization of COX-2 and iNOS in the aorta (A) and glomerulus (B) was evaluated. COX-2 (green) and iNOS (red) and their colocalization (yellow) were indicated by arrows. In both the aorta (C) and glomerulus (D), the protein content of COX-2 and iNOS could not be detected in the control group, increased sharply with obvious colocalization in the diabetes group and reduced significantly with weakened colocalization in the diabetes + urate group. Data were means ± SD (n = 5 in each group, repeated twice). *P < 0.05 or **P < 0.01 versus the diabetes group. AU, arbitrary units.

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Molecular Medicine

ISSN: 1528-3658