Table 4 Common haplotypes estimation using different SNPs from the APOE/C1/C2/C4gene cluster and their association with LDL-C, apoB, HDL-C, and apoAI.

(%)

Mean (SE)

Mean (SE)

A1 (ε3)

1^b

1

1

1

1

2^c

1

—

—

—

28.93

3.11 (0.03)

0.90 (0.01)

A2 (ε3)

2

1

1

2

1

1

1

—

—

—

27.11

3.09 (0.03)

0.89 (0.01)

A3(ε4)^d

2

2

1

1

2

1

1

—

—

—

10.93

3.27 (0.04)^e

0.92 (0.01)

A4 (ε3)

1

1

1

2

1

1

1

—

—

—

4.81

3.07 (0.06)

0.89 (0.02)

A5 (ε2)^f

1

1

2

1

1

1

—

—

—

4.43

2.67 (0.07)^e

0.81 (0.02)^e

A6 (ε3)

2

1

1

1

1

2

1

—

—

—

4.32

3.11 (0.07)

0.91 (0.02)

A7 (ε2)^f

1

1

2

1

1

1

1

—

—

—

3.98

2.65 (0.07)^e

0.79 (0.02)^e

A8 (ε3)

1

1

1

1

1

1

—

—

—

3.05

3.23 (0.08)

0.93 (0.02)

A9 (ε3)

1

1

1

1

1

1

1

—

—

—

2.22

3.10 (0.10)

0.88 (0.02)

A10 (ε3)

1

1

1

1

1

2

2

—

—

—

2.20

3.09 (0.09)

0.87 (0.02)

HDL-C

apoAI

(%)

Mean (SE)

Mean (SE)

B1 (ε3)

—

1

1

—

—

1

1

1

—

—

28.21

1.70 (0.02)

1.63 (0.01)

B2 (ε3)

—

1

1

—

—

2

1

1

—

—

28.14

1.67 (0.02)

1.61 (0.01)

B3 (ε3)

—

1

1

—

—

1

1

2

—

—

11.82

1.77 (0.02)^g

1.67 (0.01)^g

B4 (ε4)^d

—

2

1

—

—

1

1

1

—

—

6.49

1.63 (0.03)^g

1.58 (0.02)^e

B5 (ε4)^d

—

2

1

—

—

1

1

2

—

—

5.60

1.68 (0.04)

1.63 (0.02)

B6 (ε3)

—

1

1

—

—

2

1

2

—

—

5.28

1.73 (0.04)

1.65 (0.02)

B7 (ε2)^f

—

1

2

—

—

1

1

1

—

—

4.26

1.69 (0.04)

1.64 (0.02)

B8 (ε2)^f

—

1

2

—

—

1

2

2

—

—

2.80

1.82 (0.05)^g

1.70 (0.03)^e