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Table 1 Genes located in the 1.4-Mb microdeletion.

From: Identification of Genes Potentially Involved in the Increased Risk of Malignancy in NF1-Microdeleted Patients

Gene Symbola

Alternative symbols

GenBank accession number

Location at 17q11.2 (kb)

Orientation: Sense (+); Antisense (−)

Gene name

LRRC37B2

DKFZp667M2411

NM_207323

25,959–25,966

+

Leucine rich repeat containing 37, member B2

SUZ12P b

LOC440423, JJAZ1-P

BC041912

26,082–26,121

+

Suppressor of zeste 12 homolog pseudogene

CRLF3

CYTOR4

NM_015986

26,175–26,133

Cytokine receptor-like factor 3

LOC646013 b

XR_017620

26,182–26,183

+

LOC646013 similar to 40S ribosomal protein S17

ATAD5

FLJ12735

NM_024857

26,183–26,246

+

ATPase family, AAA domain containing 5

C17orf42

FLJ22729

NM_024683

26,257–26,250

Chromosome 17 open reading frame 42

CENTA2

HSA272195

NM_018404

26,273–26,310

+

Centaurin, α2

RNF135

MGC13061

NM_032322

26,322–26,351

+

Ring finger protein 135

DPRXP4 b

AC138207

26,326–26,327

+

Divergent-paired related homeobox pseudogene 4

LOC646021

XM_933339

26,356–26,396

+

LOC646021 hypothetical LOC646021

LOC646037

XM_928998

26,404–26,399

LOC646037 similar to CG11835-PA

NF1

NM_000267

26,446–26,725

+

Neurofibromin 1

OMG

OMGP

NM_002544

26,648–26,645

Oligodendrocyte myelin glycoprotein

EVI2B

NM_006495

26,665–26,654

Ecotropic viral integration site 2B

EVI2A

NM_014210

26,672–26,668

Ecotropic viral integration site 2A

AK3P1 b

X60674

26,696–26,697

+

Adenylate kinase 3 pseudogene 1

RAB11FIP4

Rab11-FIP4

NM_032932

26,742–26,889

+

RAB11 family interacting protein 4 (class II)

MIRN193A

hsa-mir- 193a

MI0000487

26,911–26,911

+

MicroRNA 193a

MIRN365-2

hsa-mir-365-2

MI0000769

26,926–26,926

+

MicroRNA 365-2

C17orf79

HSA272196

NM_018405

27,210–27,203

Chromosome 17 open reading frame 79

UTP6

HCA66, C17orf40

NM_018428

27,252–27,214

UTP6, small subunit (SSU) processome component

SUZ12

JJAZ1, KIAA0160

NM_015355

27,288–27,352

+

Suppressor of zeste 12 homolog (Drosophila)

LRRC37B

LOC114659

NM_052888

27,372–27,404

+

Leucine-rich repeat containing 37B

  1. aEntrez gene symbol.
  2. bPseudogene.