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Figure 7 | Molecular Medicine

Figure 7

From: High-Glucose Environment Inhibits p38MAPK Signaling and Reduces Human β-3 Expression in Keratinocytes

Figure 7

The phosphorylated p38MAPK expression of cultured human keratinocytes after indicated treatment condition. (A) The protein expressions of phosphorylated p38MAPK in keratinocytes with or without TLR-2-agonist stimulation were evaluated. A representative blot from three independent experiments with similar results is shown. (B) The densitometric analysis of (A), ratio of phosporylated p38MAPK/GAPDH, with 6 mmol/L glucose treatment representing 100%. (C) The effects of AG, an inhibitor of advanced glycation end-product, on protein expression of phosphorylated p38MAPK expression of high glucose-cultivated keratinocyte. The figure shown is representative of blots from three independent experiments with similar results. (D) Densitometric analysis of (C), ratio phosphory-lated p38/GAPDH, with 6 mmol/L glucose treatment representing 100%. *P < 0.05.

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