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Figure 5 | Molecular Medicine

Figure 5

From: Inhibition of Aldehyde Dehydrogenase 2 by Oxidative Stress Is Associated with Cardiac Dysfunction in Diabetic Rats

Figure 5

(A) Western blots of ALDH2 expression from control (Con), untreated diabetic (Dia), diabetic treated with NAC (NAC) and diabetic treated with α-LA (α-LA) rats. β-actin was an internal control. *P < 0.05 versus control group; **P < 0.05 versus diabetic group. Results are presented as mean ± SEM (n=6–8). (B) Representative immunohistochemistrical staining for 4-hydroxy-2-nonenal (HNE)-protein adducts from Con, Dia, NAC and α-LA rats. Scale bar, 50 µm. (C) Western blots of Mn-SOD protein expression from Con, Dia, NAC and α-LA rats. β-actin was an internal control. *P < 0.05 versus control group; **P < 0.05 versus diabetic group. Results are presented as mean ± SEM (n = 6–8).

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