Figure 5From: New Insights of an Old Defense System: Structure, Function, and Clinical Relevance of the Complement SystemScheme of diseases in which complement has a major impact. ALS, amyotrophic lateral sclerosis; ALI, acute lung injury; ARDS, adult respiratory distress syndrome; MPGN, membranoproliferative glomerulonephritis; SLE, systemic lupus erythematosus; aHUS, atypical hemolytic uremic syndrome; MODS, multiple organ dysfunction syndrome. Adapted by permission from Macmillan Publishers Ltd: Ricklin D, Lambris JD. (2007) Complement-targeted therapeutics. Image reprinted with permission from Nat. Biotechnol. 25:1265–75.Back to article page