Figure 2From: Analysis of Potential Biomarkers and Modifier Genes Affecting the Clinical Course of CLN3 DiseaseComparison of clinical scoring of CLN3 patients with rapid (n = 2) versus slow disease progression (n = 2). Clinical scoring is shown in red for patients with rapid disease progression (patient 1, solid line; patient 2, broken line) and in blue for patients with slow disease progression (patient 3, solid line; patient 4, broken line). The shaded area represents the range between the 10th and 90th percentile calculated from clinical scoring of 25 patients who are homozygous for the 1-kb deletion in the CLN3 gene (including the two patients with rapid and slow disease progression).Back to article page